Pesticides targeting disease-carrying mosquitoes are tapping into nature’s last defense mechanism: evolution. Mosquitoes in Cambodia and Vietnam are increasingly developing mutations that make them resistant to commonly used insecticides, scientists reported Wednesday.

of ReportHe tells his story in the journal Science Advances Egyptian templesVector for dengue, yellow fever, chikungunya, zika and other diseases. The researchers found that 78 percent of the mosquitoes sampled in Cambodia and Vietnam had a mutation that, in laboratory studies, showed resistance to permethrin, a class of insecticides called pyrethroids.

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That mutation has been seen before, but not with such frequency in mosquito populations. The new study found that mosquitoes in Cambodia’s capital, Phnom Penh, had multiple mutations that made them highly resistant to two different insecticides. One insecticide spray killed only 10 percent of the mosquitoes, while the other killed none.

Insecticide resistance in mosquitoes It is becoming a public health concern.Especially as the population Egyptian temples And other species are growing and expanding due to climate change, urbanization, and globalization.

The new study underscores the need to adapt as much as possible to combat mosquitoes.

The study also shows the epidemiology and evolution of SARS-CoV-2. of Corona virus It has been frequently modified in ways that increase its circulation and allow it to avoid antibodies induced by vaccination or pre-infection.

“I believe our work will help us understand the powerful force of evolution,” said Shinji Kasai, the lead author of the study. Director of the Division of Medical Entomology at Japan’s National Institute of Infectious Diseases said in an email.

Although this mutation in mosquitoes is still limited to Southeast Asia, Egyptian temples He is a strong traveler. She lays eggs that can last for months in dry conditions and can be distributed through international trade channels, Kasai said.

“Aedes mosquitoes can live anywhere. They like artificial water reservoirs, including pots, used tires, plastic cups, basins and granules,” he said. “I think it is impossible to get rid of such reservoirs.”

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Although the mutation has not been detected anywhere in Southeast Asia outside of Vietnam and Cambodia, the report notes that it may be spreading to other parts of Asia. Mosquito-borne diseases.

Dengue infections have increased 30-fold in the past half-century, and modelers estimate there are 390 million annual infections, according to a report by Kasai and 26 co-authors.

Kasai Mosquitoes with this mutation are less likely to thrive in areas where pyrethroid insecticides are not used, they said. And it paints a picture of the long war between humans and mosquitoes — one that the bugs don’t fully expect. Destroyed.

“All organisms live as cogs on this planet and may be necessary to sustain the planet,” he said in an email. “I think the most desirable world is one where mosquitoes can be controlled to the point where people don’t need to be exposed to mosquito-borne diseases.”

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