A new opioid drug to enter the market

Some are concerned about the cost and potential side effects of the new opioid reversal drug

of Food and Drug Administration He approved a new drug to reverse opioids and the powerful synthetic opioid fentanyl, a major driver of the nation’s drug crisis.

drug maker, Separately, He’s touting the powerful nasal spray as a way to quickly save lives, preventing overdoses for hours.

But not everyone is happy. As our partner David Ovalle According to reports, there is some pushback toward the drug from public health experts, physicians and community groups. They have expressed concern about the cost of the new drug — especially with cheaper opioid antidote drugs on the market — and the possibility that some users may experience long-lasting withdrawal symptoms.

This comes as federal and state health officials struggle. Amazing number Drug overdoses continue to account for 100,000 deaths per year. The crisis has sparked a debate in Congress and the public health community about what policies are effective tools to curb the death toll — with House Republicans voting this week on a fentanyl bill. (More on that below.)

The new drug is called Indivior SweepingIt is a spray version of Nalmafene and is available in the fall.

But how much does the drug cost? By David: The company did not disclose the price of the drug. Indivor predicted 150 million to 250 million dollars It is on sale annually and is targeting the drug at health departments, fire and law enforcement agencies and school districts.

In the statement Mark CrossleyCEO of the pharmaceutical company, It is called FDA certification “Major breakthrough in development of new treatment options” to address opioid overdose.

However, more powerful reversal drugs like nalmafene are more effective than naloxone — the drug commonly used to reverse opioid overdoses — and there is some doubt that its potency may cause longer-lasting withdrawal symptoms. One population that could be a major market for the drug is youth who are intolerant to opioids.

• Utah State Sen. Jane Plumb (D), who founded the organization Utah Naloxone; She told David that she believed the company was “trying to control capital out of fear … pouring money into places.”
• Meanwhile, Crosley says, “It’s about finding the right options; I think we’ll let the first responders, the patients, and the market choose.

The new drug’s benefits came as lawmakers debated legislation in the House yesterday to permanently reclassify fentanyl-like substances as dangerous drugs.

The White House has said it has “long-standing support” of two key provisions of the bill, although the president has not said whether he will sign or veto the measure – left by lawmakers at a House Rules Committee meeting yesterday afternoon.

The Biden administration has proposed provisions in the law to permanently classify all fentanyl-related substances as Schedule I drugs.

“These two provisions are critical components of the Biden-Harris administration’s 2021 recommendations to Congress to combat illegal FRS delivery and save lives.” White House in a Statement of management policy on the HALT Fentanyl Act, The House is slated to vote on Thursday.

The statement added this line: “The administration’s 2021 recommendations to Congress include additional provisions to improve public safety.” The administration is calling on Congress to pass all of these critical measures to improve public safety and save lives.

In September 2021, The White House has presented proposals to Congress on fentanyl-related substances, including those that would buy these substances with minimum penalties other than death or serious bodily injury. Some senior Democrats worry that the bill will not include these policies.

Bloomberg News’ Alex Ruff:

In the post-Roe case, many women join the lawsuit against Texas

Eight more are women. joining the case against the Texas state abortion ban, arguing that the law prevents women from accessing the procedure, even if they have complicated — and sometimes life-threatening — pregnancy conditions.

The new plaintiffs added their names. charge First, in March, five women and two doctors filed a lawsuit against the state’s abortion restrictions, which make it a crime to perform an abortion unless the patient is pregnant. Life or serious health is in danger.

The Center for Reproductive Rights, which represents the plaintiffs, is now seeking a temporary injunction to block the state’s abortion ban on pregnancy complications, as a legal challenge to it plays out Improved complaint In a lawsuit filed yesterday in District Court in Travis County.

The lawsuit also asks the court to clarify whether doctors can make exceptions to the state ban and under what circumstances. Unlike the plaintiffs, the vague language could have led to doctors losing their licenses, being fined, and possibly facing civil and criminal charges for performing life-saving obstetrics.

CBS Austin’s Melanie Torre:

Elderly people are flooding homeless shelters without caregivers.

Shelters across the country are struggling to cope with elderly Americans in homelessness, many of whom require more advanced care than the nation’s social safety net can provide, The Post’s Christopher Rowland Reports.

Communities are scrambling to come up with new solutions to the problem, including establishing senior shelters that provide tailored medical and social services for seniors and hiring specially trained professionals to manage the daily needs of homeless seniors.

A closer look: Doctors and advocates describe the cycle, which they say makes the elderly especially vulnerable to life on the streets. Homeless people are diagnosed with chronic diseases and other geriatric problems much earlier than average, and elderly patients often take longer to recover. However, Medicaid only pays for long-term nursing home care or if a person is unable to care for themselves—a condition that many elderly homeless people are unable to afford.

Because of this, health professionals in Phoenix call “cure and street” the homeless patients who often return to shelters or their walk-up tents after being treated for serious illness by hospitals. ,” Christopher wrote.

Why is it important? Federal government Assumptions About a quarter of a million people who are 55 and older At least part of the United States was homeless in 2019.

After a recent infant death, care at US border facilities is being reviewed.

The deaths of three migrant children in U.S. government custody this year prompted a review of health care practices. Customs and Border ProtectionOur partner Nick Miroff Reports.

The agency reviews all “medically fragile” individuals under its care. Troy MillerActing Commissioner of CBP said press release.

The details are: An 8-year-old immigrant girl who crossed the border into the United States in South Texas fell ill with the flu last Wednesday. As her medical history, including sickle cell anemia and heart disease, worsened, federal authorities did not send her to the hospital where she was arrested.

A few days ago, May 10, A 17-year-old Honduran boy died while staying at a Florida shelter for unaccompanied minors and children crossing the border. A 4-year-old girl from Honduras who had been in the agency’s care since 2019 died on March 17 after going into cardiac arrest, the federal health department confirmed. She was also considered “medically frail”.

The big picture: The recent deaths have focused attention on U.S. medical care and treatment for migrant teenagers and children in government custody, and are highlighting the dangers to U.S. agents and workers at border facilities overwhelmed by the number of illegal crossings. CBP officials say they have greatly improved medical care and screening procedures in recent years, Nick wrote.

Rep. Raul M. Grijalva (D-Ariz.):

• New this: General surgeon Vivek Murthy He took it out. New advice The impact of social media use on youth mental health.
• Abortion at 12 weeks pregnant is now banned in Nebraska after Republican Gov. Jim Pillen A new ban was signed It was implemented immediately yesterday. The law restricts gender-affirming care to people under the age of 19 in the state, effective Oct. 1. Omaha World-HeraldS Erin Balmer Reports.
• Some patient advocates They criticized that. A National Institutes of Health-funded trial to study exercise as a long-term treatment option for Covid-19. They argue that such an experiment could be dangerous for long-term patients with chronic fatigue syndrome because it shows that physical activity worsens symptoms, The Post’s Amanda Morris Reports.

Funders thought watching bats wasn’t necessary. She then helps solve the mystery of a deadly virus. (By Caroline Chen | ProPublica)

Covid-19 loan fraud probes lead to bankers letting them down (by Ben Penn | Bloomberg Law)

How Tuberville’s Blockade of Pentagon Nominees Could End (By Joe Gould and Conor O’Brien | Politics)

Thanks for reading! See you all tomorrow.