Summary: Seven percent of patients with dementia had chronic kidney disease, and 9 percent had albuminuria, a urine marker for kidney disease. Chronic kidney disease increases the risk of dementia by 51%.

Source: American Society of Nephrology

New research has confirmed the relationship between kidney disease and the development of cognitive problems.

The findings will be presented at ASN Kidney Week 2022 from November 3 to November 6.

The study was based on data from the population-based Framingham Heart Study. Among the 2,738 participants without dementia, 187 (7%) had chronic kidney disease and 251 (9%) had albuminuria, a urinary symptom of kidney disease.

Albuminuria is associated with silent stroke symptoms, and patients with albuminuria are 65% more likely to develop mild cognitive impairment or dementia.

Chronic kidney disease was not associated with markers of silent cerebrovascular disease, but was associated with a 51% higher risk of developing dementia.

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“Our results highlight the importance of albumin as a cerebrovascular and cognitive risk factor and suggest that there may be additional shared disease mechanisms in the kidney and brain in addition to hypertension,” said corresponding author Derbhala Kelly, MBBChBAO, MSc, DPhil, St. The James Hospital, Dublin, Ireland.

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Author: Christine Feheley
Source: American Society of Nephrology
Contact: Christine Feheley – American Society of Nephrology
Image: The image is in the public domain.

Preliminary study: The findings will be presented at ASN Kidney Week 2022