Summary: Older women who walk or participate in moderate to vigorous physical activity every day are less likely to develop mild cognitive impairment and dementia.
A new study led by California Sun University’s Herbert Wertheim School of Public Health and Human Longevity Sciences suggests that older women are less likely to develop mild cognitive impairment or dementia if they walk daily and do moderate to vigorous physical activity. Diego.
Online edition on January 25, 2023. Alzheimer’s and Dementia: Journal of the Alzheimer’s AssociationThe team found that women aged 65 and older had a 21 percent lower risk of mild cognitive impairment or dementia for each additional 31 minutes of moderate to vigorous physical activity per day. For every additional 1,865 daily steps taken, the risk was 33 percent lower.
Senior author Andrea Lacroix, PhD, MH, Distinguished Professor, said: “Given that the onset of dementia can begin 20 years or more before symptoms appear, early intervention is essential to delay or prevent cognitive decline and dementia in older adults.” Herbert Wertheim School of Public Health and Human Longevity Sciences at UC San Diego.
Although there are many types, dementia is a neurological disease that impairs the ability to remember, think, solve problems or reason. Mild cognitive impairment is primary memory loss or thinking problems that are not as severe as dementia.
According to the United States Department of Health and Human Services, dementia affects more than 5 million people in this country. This number is expected to double by 2050.
More women than men live with and have a higher risk of dementia.
“Exercise has been identified as one of the three most promising ways to reduce the risk of dementia and Alzheimer’s disease. Once dementia is diagnosed, it is very difficult to slow or reverse it, so prevention is important. There is no cure,” said Lacroix.
However, few large-scale studies have considered the instrument’s mobility and sitting measures in patients with mild cognitive impairment and dementia, and most of the published information on exercise and competitive behavior is based on cognitive decline and dementia. said first author Steven Nguyen, PhD, MPH, a postdoctoral scholar at the Herbert Wertheim School of Public Health.
For this study, the researchers used data from 1,277 women as part of two Women’s Health Initiative (WHI) ancillary studies – the WHI Memory Study (WHIMS) and the Objective Physical Activity and Cardiovascular Health (OPACH) study. The women wore a research-backed accelerometer device and performed their daily activities for up to seven days with precise exercise and sitting.
The activity trackers showed the women averaged 3,216 steps, 276 minutes of light exercise, 45.5 minutes of moderate-to-vigorous exercise, and 10.5 hours of sitting per day. Examples of light physical activity might include housework, gardening, or walking. Moderate to vigorous exercise can include brisk walking.
The study found that high amounts of sitting and long periods of sitting were not associated with mild cognitive impairment or dementia.
Together, this information has clinical and public health significance, as there is little published data on the amount and amount of physical activity needed to lower dementia risk, Nguyen said.
“Seniors can be encouraged to increase at least moderate-intensity activity and take extra steps every day to reduce the risk of mild cognitive impairment and dementia,” Nguyen said.
“The daily steps findings are particularly interesting because steps are recorded by a variety of wearable devices that individuals increasingly wear and can easily carry.”
The authors said that more research is needed among different populations that include men.
Co-authors include: John Bellettiere, UC San Diego; Kathleen M. Hayden and Stephen R. Rapp, Wake Forest University School of Medicine; Chongzhi Di, Fred Hutchinson Cancer Center; Praia Palta, Columbia University Irving Medical Center; Marcia L. Stefanik, Stanford University School of Medicine; Joan E. Manson, Harvard Medical School; and Michael J. LaMonte, University at Buffalo – SUNY.
Financial support This research was partially funded by the National Institute on Aging (P01 AG052352, 5T32AG058529-03) and the National Heart, Lung, and Blood Institute (R01 HL105065). The Women’s Health Initiative is supported by the National Heart, Lung, and Blood Institute (75N92021D00001, 75N92021D00002, 75N92021D00003, 75N92021D00004, 75N902021D).
So Exercise, Aging and Dementia Research News
Author: Yadira Galindo
Contact: Yadira Galindo – UCSD
Image: The image is in the public domain.
Preliminary study: Closed access.
“Accelerometer exercise and incidental sitting in elderly women with mild cognitive impairment or dementia” by Andrea LaCroix et al. Alzheimer’s and dementia
Accelerometer exercise and incidental sitting in elderly women with mild cognitive impairment or dementia
Physical activity (PA) is inversely associated with dementia risk, but few studies have examined PA accelerometers and are strongly associated with risk of mild cognitive impairment (MCI) and dementia.
We examined accelerometer measures (PA and sitting) in women with spontaneous MCI/probable dementia in a women’s health initiative.n = 1277; (mean age = 82 ± 6 years).
During a median follow-up of 4.2 years, 267 MCI/probable dementia cases were identified. Adjusted Cox regression HRs (95% CI) for moderate-to-vigorous PA (MVPA) min/d quartiles were 1.00 (reference), 1.28 (0.90 to 1.81), 0.79 (0.53 to 1.17), and 0.69 (0.045) for 1.00. ; P-trend = 0.01. Adjusted HRs (95% CI) by stage/D quartiles were 1.00 (reference), 0.73 (0.51 to 1.03), 0.64 (0.43 to 0.94), and 0.38 (0.23 to 0.61). P-trend <0.001. The HR (95% CI) for each 1-SD increase in MVPA (31 min/d) and steps/d (1865) were 0.79 (0.67 to 0.94) and 0.67 (0.54 to 0.82), respectively. Sitting was not associated with MCI/probable dementia.
The findings suggest that ≥ moderate intensity PA, particularly stair climbing, is associated with a lower risk of MCI and dementia.