If you’re considering getting an Omicron-based covid booster vaccine, you’re probably wondering what the side effects are and how severe they might be.

Rest assured: They shouldn’t be too different from what you’ve experienced in the past with vaccines and booster shots.

“We have no information on this. [yet]Essentially giving two vaccines in one injection – but biologically, I just don’t expect the side effects, severity or safety profile of the shot to be any different than the current MRNA vaccines and boosters,” said Dr. Paul Offitt, director of the PRES. Center for Immunization Education at the Children’s Hospital of Philadelphia and a member of the U.S. Food and Drug Administration’s Independent Advisory Panel, tells CNBC Make It.

The modified vaccines from Pfizer and Moderna are bivalent, meaning they target both the original strain of Covid and the omicron BA.5 and BA.4 sub-variants. Because of the approval of the new incentives, side effect information is not yet available FDA And Centers for Disease Control and Prevention Before fully completing clinical trials.

Federal agencies based their approval on a number of other safety data, including data from the first Covid vaccines — the updated formulations are only for those first changes — and lab data on the shot’s BA.5 ingredient in mice.

They also examined clinical trial data on earlier versions of bivalent stimulants targeting omicron’s BA.1 subunit. Those shots were never released to the public, as the BA.1 was quickly outclassed by other omicron sub-variants – but their design is very similar to the photos. It is now available in pharmacies and clinics nationwide..

Together, the evidence provides a road map for the side effects you can expect after receiving one of the new stimulants, and how severe those side effects might be.

Expected side effects

in Pfizer And Modern For clinical trials of BA.1 vaccines, participants who were already fully vaccinated with a booster received an improved booster dose. In both clinical trials, the most commonly reported side effects within seven days of receiving the vaccine were:

  • Pain
  • Fatigue
  • Headache
  • Muscle pain
  • Chilling
  • Joint pain
  • Redness and swelling at the injection site
  • Fever

That’s a familiar list: the same group of side effects that came with the original formulas. But especially in those clinical trials, the severity of side effects was very light.

Pfizer’s trial showed that 52% of participants who received the BA.1 shot experienced mild pain at the injection site, 8% experienced moderate pain and only 0.3% experienced severe pain. Approximately 26% of participants experienced mild or moderate headache, and only 0.3% experienced severe pain.

Moderna’s trial showed that about 59% of participants experienced fatigue, but only about 4% experienced that at grade 3, which is defined as significant fatigue that interferes with daily activities.

Serious side effects are “generally” more common after the second vaccination, not after the third or fourth dose, Offit says. They are only eligible for the new boosters if they have completed the primary vaccination series, which means most people will have already received at least two doses.

Same concept The truth was held during the last round of incentive shots. The new vaccines have similar dosages to the original vaccines, which suggests their safety profiles may be similar, Offit said.

Contains one dose of Pfizer monovalent vaccine 30 micrograms The mRNA that targets the first covid strain. Updated booster shots cHave the same number of micrograms15 target first level and other 15 target BA.4 and BA.5.

It contains the Moderna monovalent shot 50 micrograms of mRNA targeting the original strain per dose. His Updated encouragement 25 micrograms targeting the first species and 25 micrograms targeting subspecies.

The BA.1 trials only tested a few hundred people, a relatively small sample compared to the thousands of Americans set to receive the new BA.5 dose, Offit notes. He says you can still be sure you’re in – just don’t be 100% sure what to expect.

“We have to keep our eyes open as to what side effects and adverse events may occur and keep in mind that this is still a new product,” says Offit.

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