Harmful chemicals in consumer and industrial products are contributing to an increase in liver disease in children, according to a new study.

The study was conducted by researchers at Mount Sinai and on Wednesday JAMA Network Open, Is an early overview of chemicals that disrupt the endocrine system during pregnancy and the recent increase in non-alcoholic fatty liver disease (NAFLD) in children. It has been shown that infants who are most exposed to such chemicals during pregnancy have higher levels of biomarkers, which indicates an increased risk of liver disease.

Endocrine disruptive chemicals are a type of environmental pollutant that is found in cooking, packaging, household items, baby products, pesticides and others that disrupt the endocrine system, producing and producing hormones. They include a group of chemicals known as PFSIt is also called “Chemicals Forever” The reason for how long they stay in the area.

In 2009, 36 out of 100,000 children, compared to 58.2 per 100,000 in 2018, the number of NAFLDs in children increased steadily. A.D. Research published in Pediatrics in 2020. Of American Liver Foundation Currently, 10% of all American children have NAFLD and 38% are obese American children.

“Children with chronic disease are particularly vulnerable and have poor prognosis, including the need for liver transplantation during adulthood,” the foundation said. A press release on the study emphasized that NAFLD in children can lead to chronic liver disease and liver cancer during adulthood.

Mount Sinai explorers Between 2003 and 2010, the study first measured 45 endorphins, including PFAS, in the blood or urine of 1,108 pregnant women, and children between the ages of 6 and 11 were measured by researchers. Biomarkers in the blood that indicate a risk of liver disease. High susceptibility to chemicals in the uterus is associated with higher biomarkers. The study also showed that similar chemicals are passed between mothers and babies through the uterus before and after birth, with breast milk.

“We are all exposed to these chemicals every day through the food we eat, the water we drink and the consumption of consumer products.”

“These findings suggest that prenatal exposure to endocrine-disruptive chemicals increases the risk of non-alcoholic fatty liver disease in children,” she added.

Although almost everyone in their lifetime is exposed to endocrine disruptive chemicals, early exposure – including in the womb – increases a baby’s NAFLD, according to Valvey.

Obesity and genetics increase the risk of developing NAFLD in children, but these factors do not explain how rapidly the disease has increased, says Dr. Robert Wright, co-author of the study and co-director of the Icahn Exposomatic Research Institute. Mount Sinai spoken today.

“Genetics cannot explain the epidemic in 20 to 30 years. It takes many generations for genes to change the course of the disease, and only something in the environment can explain the rapid changes. … We have never seen so much liver disease in children before, ”said the director.

What can parents do about prenatal chemical exposure?

One way for future parents to reduce the risk of developing fetuses being exposed to endocrine disruptors is to avoid using products such as plastic containers, bottles, packaged foods and beverages, and processed foods, Valvey said. “Eat as much fresh and organic food as possible,” she advised.

Valve did not offer specific brands to remove it, but the American Academy of Pediatrics has recommended it. Reducing the risk of PFAS. And has resources for disease control and prevention centers PFS And PBDsThe study looked at another group of chemicals.

Wright also suggests that young children, in particular, have low blood sugar levels and should exercise regularly to prevent obesity. “Obesity was very rare in children during my 90’s,” he says. “(This) affects one in five children and adolescents in the US right now.” He said.

Valvey and Wright’s research hopes that policymakers will understand the importance of preventing endorphins from consuming consumer products and help companies make informed decisions about which chemicals are best described on products and packaging. “By understanding the environmental factors that accelerate the spread of fatty liver disease, we can reduce people’s vulnerability by providing factual information,” Wright said.

In the meantime, Valvey emphasized the need for further studies such as “Understanding how environmental chemical exposures are linked to our genes, diet, and social factors in pediatric liver disease development.”



Source link

Leave a Reply

Your email address will not be published. Required fields are marked *