A.D. In November 2021, we bring you the news of the scientists Development of cancer screening Using genetic engineering worms to identify the early signs of pancreatic cancer from a drop of urine.

Researchers at Osaka University have now discovered that microscopic worms, known as nematodes, can kill cancer cells. According to the press release At an institution published last month. To achieve this, the worms must be covered with hydrogen-based “shells,” which are used to transport additional engineering-carrying load (cancer-killing substances).

A sea worm that seeks out cancer cells

It is one of these types of nematodes Anisakis easy, Microscopic marine creatures, especially those that love cancer cells.

Anisakis easy The study’s first author, Wilden Mubarak, said in a statement that the “smell” of cancer had been identified and that it could be associated with cancer. This raises the question of whether antiretroviral therapies are effective in delivering cancer cells to the human body.

The researchers decided to test the effect of hydrogen peroxide on the nematodes to create a gel-like coating all over their body and to protect them from cancer-causing substances. The final results were nematodes covered with 0.01 mm thick cloth. Although very cold, the whole process took only 20 minutes.

“The results were very clear,” said Shinji Sakai, the study’s lead author. “The coatings did not interfere with the survival of the worms in any way and were flexible to maintain the activity of the worms and to protect their natural ability to detect odors and chemical symptoms.”

Anti-cancer agents are sent directly to cancer cells

The researchers then experimented by applying anti-cancer agents to the nematodes. Normally this can be harmful to parasites, but in this case, the creatures are protected by their hydrogel shield. Scientists confirm that the new engineering worm is transporting and delivering anti-cancer agents to kill cancer cells. In a glass.

“Our findings suggest that nematodes can be used to deliver a variety of targets for future implementation,” Mubarak said. “Considering the ability of the hydrogel membranes to adapt, this worm-based supply system has applications that can not only deliver anti-cancer drugs to patients’ tumor cells, but also deliver beneficial bacteria to other plants in other areas.”

The study is still in its infancy, and it may face a number of issues during development. There is a fact that most people do not want Dependent worms In their system. There is also the issue of how creatures are controlled after they are given to the human body. It still promises a new and effective solution in terms of cancer treatments.

The study Published In the magazine Science is straightforward.


Engineer features features of biological creatures to introduce new functions and improve their reproductive functions. However, surface engineering studies are limited to unisexual creatures. Here, the nematodes are engineered. The main place hydrogelation medium in horseradish peroxidase (HRP) back to freelancers. In this method, approximately 10-ውፍረትm thick hydrogel coatings are made from different types PolysaccharidesProteins and Artificial polymers. Caenorhabdit elegans And Anisakis easy The hydrogel coating, which is covered by the hydrogel, showed a negligible reduction in chemotherapeutics and locomotion. Hydrogel coatings UV-resistant groups and Catalasse It protects the nematodes from UV and hydrogen peroxide. The results also show that they contain hydrogel coatings Glucose oxide They have the potential to be used as a viable drug for cancer treatment. Nematodes Functionality The method developed in this study has the potential to affect a wide range of fields, from agriculture to medicine.

Source link

Leave a Reply

Your email address will not be published. Required fields are marked *