A rare, recently discovered inflammatory disease may affect more people than previously thought, new research suggests.

Scientists first discovered in the A.A.A.A.S Paper published in 2020 The New England Journal of Medicine (NEJM). At that time, only 25 men in the United States were diagnosed with the disease – and no women. They all had the same mutation in a gene called UBA1.

Now, new Paper published in Jama On January 24VEXAS, while still rare, is much more common than scientists initially believed, affecting about 1 in 13,600 people. The researchers found that VEXAS is more common in older individuals and affects both men and women: Among those 50 and older, researchers estimate the prevalence of VEXAS to be about 1 in 4,300 men and 1 in 26,200 women.

VEXAS usually occurs in people with other autoimmune conditions, including lupus, rheumatoid arthritis, and leukemia.

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